Pharmacological Use of NLRP3 Inflammasome Inhibitors: Novel Intervention Strategies in Diabetes-Associated Vascular Complications
نویسندگان
چکیده
NLRP3 inflammasome has emerged as a key regulator of glucose and insulin homeostasis. Several studies have shown that activation of the NLRP3 inflammasome contributes to obesityinduced inflammation and insulin resistance [1]. Increased oxidative stress may also contribute to NLRP3 inflammasome activation during diabetes and its complications [2]. The NLRP3 inflammasome is a complexe that consists of NLRP3, the
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